Research Stream: Epidemiology and Clinical Trials

Research

The association between vitamin D status and brain outcomes

In collaboration with Professor Darryl Eyles, we are measuring early life vitamin D deficiency status and exploring if this changes the risk of later developing serious mental illness. These studies are in collaboration with colleagues in Denmark, Sweden and the Netherlands.

The demographic and clinical correlates of psychotic-like experiences

Using two large surveys conducted in Australia in 1997 and 2007, our group have undertaken a suite of students designed to understand the clinical relevance of isolated psychotic-like experiences. Over recent years we have published many papers on this topic, and have made important contributions with respect to how psychotic-like experiences are associated with (a) an increased risk of later psychotic disorder, (b) depression, anxiety and substance use disorders, (c) a family history of mental illness, (d) exposure to trauma, (e) an increased risk of suicidal ideation and behaviour, (f) general physical health, and (g) help-seeking.

The Survey of High Impact Psychosis (SHIP)

Our group was one of seven sites involved in the design and administration of the second Australian Survey of psychotic disorders. In collaboration with a large national team, we continue to explore key issues related to the needs of people with psychosis in Australia.

Clinical Trials

Professor John McGrath was awarded a John Cade Fellowship in Mental Health Research by the National Health and Medical Research Council (NHMRC) in 2013. The Fellowship will enable Professor McGrath and his team to build a clinical trials platform in South-East Queensland. These trials, collectively known as Cadence, will be broadly related to improving clinical outcomes for people with psychosis, particularly early psychosis.

Cadence BZ Trial

Can sodium benzoate, a commonly used food preservative, assist with recovery from psychosis?

Cadence M Trial

Can an extract from the tropical fruit mangosteen assist in the treatment of schizophrenia?

Cadence SCIT Trial

Can social cognition interaction training assist in the treatment of schizophrenia?