BURDEN OF DISEASE

The Global Burden of Disease Study 2010 (GBD 2010)

The Global Burden of Disease Study 2010 (GBD 2010) is the largest systematic effort to describe the global distribution, mortality and disability presented by major diseases, injuries, and risk factors. The scope of the study encompassed 291 causes from 187 countries and 21 world regions. This covered the entire lifespan as well as 20 separate age groups, both genders and persons in total, and provided estimations of trends from 1990 to 2010.

Led by Harvey Whiteford and Louisa Degenhardt (UNSW, Australia) along with Amanda Baxter as Project Manager, the Mental Disorders and Illicit Drug Use Expert Group was responsible for the mental and illicit drug use disorders included in the study. As the core body in this group, PEABOD assembled the data and worked on the analyses for this component of the study while simultaneously liaising with the Institute of Health Metrics and Evaluation at the University of Washington (coordinating centre) as well as a number of other institutions and experts from around the world. The spread of responsibilities between the PEABOD members is listed below:

Amanda Baxter (Project Manager)

  • Anxiety disorders
  • Autism
  • Asperger’s disorder
  • Amphetamine dependence
  • Cocaine dependence

Alize Ferrari

  • Major depressive disorder (MDD)
  • Bipolar disorder
  • Schizophrenia
  • Cannabis use and dependence
  • Mental, illicit drug use, alcohol use disorders as a risk factor for suicide

Holly Erskine

  • Conduct disorder
  • ADHD
  • Anorexia Nervosa
  • Bulimia Nervosa

Fiona Charlson

  • Dysthymia
  • Opioid dependence
  • Injecting drug use (IDU)
  • MDD as a risk factor for ischemic heart disease (IHD)

Preliminary results were released in a special, triple issue of the Lancet in December 2012 (see Publications) with papers analysing the burden of individual mental disorders either currently under review or in progress.

In August 2013, two papers were published by the Lancet reporting the global burden of mental and substance use disorders and the global burden of illicit drug use disorders (see Publications). To download an infographic detailing the main findings of both papers, see: http://press.thelancet.com/GBDinfographic.mp4  (Acknowledgement: The Lancet, 2013).

The Global Burden of Disease Study 2.0 (GBD 2.0)

The GBD Study will be updated annually with continuing improvements to methodology as well as an expansion of the number of diseases, injuries and risk factors investigated. PEABOD will be involved in the continuing updates of the mental and illicit drug use disorder component of GBD.

Publications