Does adult vitamin D deficiency lead to altered brain function?

Animal experiments have demonstrated that a wide range of prenatal exposures, including low vitamin D levels, can impact on the behaviour of the offspring. We have now shown that low vitamin D levels during adulthood has an impact on behaviour and brain neurochemistry in rodents. These results provide the first evidence in mice to show that adult vitamin D deficiency impacts on neurotransmitter systems that are affected in a number of neuropsychiatric conditions, including autism, schizophrenia and depression. Development of this animal model will provide a platform for future investigations into the effects of vitamin D deficiency on the adult brain.